Programme

CCP4 STUDY WEEKEND 2011 - MODEL BUILDING & REFINEMENT & VALIDATION

Note that the programme will be updated as talks are confirmed and abstracts are received so please check back regularly for latest information.


Download a printable version of the programme from here... Printable Version

 

Books of Abstracts will be issued at the conference. However, in case of any problems with travel, you are able to download a copy here.

NOTE: All talks will take place in the Ramphal Lecture Theatre in the Ramphal Building

Wednesday 5 January 2011


13:00 - 17:00   Registration open in the Foyer of Scarman House
15:00 - 18:15   Diamond MX User Meeting in the tiered lecture theatre of Scarman House (see "Satellite Meetings")

Thursday 6 January 2011


08:30   Registration opens in the foyer of the  Ramphal Building
09:00  Tea and Coffee Available


PROGRAMME FOR THE MAIN EVENT

(This will be updated and refined in the run up to the Conference when titles are confirmed)

Day 1 - Thursday 6 January 2011


09:00 - 10:30 What's New in CCP4? Ronan Keegan
10:30 - 11:00 COFFEE / TEA
Session 0 - Introduction to Meeting Themes
11:00 - 11:10 Introduction to the Meeting Roberto Steiner
11:10 - 11:50 Why Protein Crystallography is (still) Difficult: an Overview of Key Challenges Bernhard Rupp
11:50 - 12:30 Using prior structural information in model building and refinement  George Sheldrick
12:30 - 14:00 LUNCH (including Lunchtime Bytes sessions) in Rootes Building
Session 1 - Building a Model: Automated, Manual, Sometimes Easy, Sometimes Not
14:00 - 14:30 Recent Developments in BUCANEER for Model Building and Refinement Kevin Cowtan
14:30 - 14:50 New Tools for Model Improvement in Coot Using Concerted Torsions Description Paul Emsley
14:50 - 15:15 New structures solved and built with ARCIMBOLDO... and a glimpse of SUBIX Isabel Uson
15:15 - 15:40 Low-Resolution Model Building Alwyn Jones
15:40 - 16:10 Coarse-Grained Models for Molecular Structure Refinement and Dynamics Willy Wriggers
16:10 - 16:45 COFFEE / TEA
Session 2 - Refining a Model: General Strategies and Novel Developments
16:45 - 17:15 Crystallographic Structure Refinement and Validation Using PHENIX Pavel Afonine
17:15 - 17:45 Recent developments in BUSTER: autoNCS, targetting, and improved ligand restraints Oliver Smart
17:45 - 18:15 Knowledge-based restraints in phenix.refine for improved macromolecular refinement at low resolution Jeff Headd
19:00 - 24:00 CONFERENCE DINNER IN THE PANORAMA SUITE, ROOTES BUILDING
(followed by entertainment and dancing)

 


Day 2 - Friday 7 January 2011


Session 3 - Refining a Model: Low-Resolution, Twinning and Complex Cases
09:00 - 09:30 Computational approaches to improve the quality of structures obtained from low-resolution diffraction data Axel Brunger
09:30 - 10:00 Low Resolution Macromolecular Crystal Structure Refinement: Problems with and Approaches To Garib Murshudov
10:00 - 10:30 Structure Solution and Refinement of Human Complement Factor I: Tetartohedral Twinning can Happen to You Too Pietro Roversi
10:30 - 11:00COFFEE / TEA
Session 4 - Ligands and Nucleic Acids: How to Properly Treat Non-Amino Acids
11:00 - 11:25 Modern Methods of Ligand Refinement and Analysis Using Coot Judit Debreczeni
11:25 - 11:45 JLigand: a Graphical Editor to Create Ligand Descriptions Andrey Lebedev
11:45 - 12:15 Challenges and Surprises that Arise with Nucleic Acids
Bill Scott
12:15- 12:40 Model completion and ligand building with ARP/wARP Victor Lamzin
12:40 - 14:00 LUNCH (including Lunchtime Bytes Sessions in Rootes Building)
Session 5 - Validation: Keep Checking You're on the Right Track
14:00 - 14:25 2 Copies Good, 4 Copies Better: Validation by Non-Crystallographic and Cross-Crystal Symmetry Frank von Delft
14:25 - 14:50 Statistical Quality Indicators for Electron Density Maps Ian Tickle
14:50 - 15:20 To B or not to B? What's appropriate in models from 1 A to 4 A (And thus the native hue of resolution is sicklied o'er with the pale cast of thought - W. Shakespeare) Ethan Merrit
15:20 - 15:50 The future of validation in the PDB Sameer Velankar
15:50 - 16:15 PDB_REDO: Constructive validation, more than just looking for errors Robbie Joosten
 16:15 - 16:30  CONCLUDING REMARKS - ALL